The Cumberland-Perry Drug and Alcohol Commission (the "Commission") operates from within the Cumberland County Human Services Building as a department of county government and as one part of a broad system of county human services. The Boards of the County Commissioners of Cumberland and Perry Counties select volunteers representing various community and geographic interests to serve on the Commission community advisory board. There are nine board representatives from Cumberland County and six representatives from Perry County. The responsibility of this group of 15 appointed members is to plan and oversee the delivery of publicly funded drug and alcohol services in the counties.

The Commission administrative staff is responsible for managing public funds for drug and alcohol services. The Commission contracts with local community-based organizations for the actual delivery of prevention, intervention, and treatment services with one exception. The Commission provides prevention and early intervention services in Cumberland County through the "in-house" Resource Center. All service providers, including the Commission Resource Center, are approved or licensed by the Pennsylvania Department of Health in accordance with the State Plan for Drug and Alcohol Services and State regulations.

Over the years the Commission has developed a continuum of care that is capable of addressing the varied needs of clients throughout the 1,100 square mile catchment area. Services include: Administration Services provided by the Commission; Prevention and Early Intervention Services provided by the Drug and Alcohol Resource Center and Perry Human Services; Detoxification Services provided by Roxbury and Common Ground; Inpatient Treatment Services; and Outpatient Evaluation and Treatment Services provided through Gaudenzia West Shore (Mechanicsburg, Newville and Carlisle), Perry Human Services (New Bloomfield), Diakon Family Life Services (Mechanicsburg), Roxbury (Carlisle and Chambersburg), and NHS Stevens Center (Carlisle).